1. Brett Favre (), 2. George Blanda (), 3. John Hadl (), 4. Vinny Testaverde (), 5. Fran Tarkenton (). Houston Texans quarterback Matt Schaub set an NFL record on Sunday, a record that no quarterback wants to set. Blake Bortles threw his 11th career pick six Sunday. Blake Bortles' 11 Pick - Sixes are the most by a QB through their 1st 3 seasons in NFL. This is a list of records in the National Football League (NFL) set by individual players. . Passing touchdowns are listed separately. Most seasons leading. In a game against the Seattle Seahawks, Thomas sacked quarterback Dave Krieg seven times. That record has stood for more than 20. Prescott, the Dallas Cowboys' starter, has extended his NFL record for rookie quarterbacks, extending his run of passes without an interception.