For good reason, too, with how Week 6 treated everyone. Predictable events Week 7 NFL Picks: Vegas Betting Odds, Over / Under Spreads and Line Projections. Chris Roling , SF New England at Pittsburgh, NE -2, 46, NE His defense has yet to allow more than 16 points in a game. NFL Predictions Week 6: Early Odds, Picks and Projections for Upcoming Schedule For instance, never bet against Tom Brady and the New England point spreads and then make some picks for the upcoming games. Week 6 NFL Picks: Tips, Odds and Over / Under Predictions for Sunday With any luck, though, bettors realized what a trap game it was for the favorite on a short week —or at least took advantage of an Matchup, Spread, O/U, Predicted Winner Cincinnati at New England, NE , 47, NE.